Il kit fornisce il materiale necessario per rilevare la presenza di Enterobatteri resistenti ai carbapenemi (CRE, carbapenem-resistant Enterobacteriaceae) e di alcuni geni codificanti per le beta-lattamasi a spettro esteso (ESBL, extended spectrum beta lactamases).
Target (β-lattamasi):
- AmpC β-lactamase pan-CMY (include CMY-2, 4, 16, 31, 48, 59 e 73)
- CTX-M group 1 (CTX-M-1, 3, 12, 14, 15, 28, 29, 32, 36, 54, 55, 58, 79 e 103)
- CTX-M group 9 (CTX-M-9, 13, 14, 24, 27, 38, 65 e 93)
- β-lactamase GES
- Metallo β-lactamase VIM (include VIM da 1 a 7, 11, 19 e da 36 a 40)
- Metallo β-lactamase IMP (include IMP-1, 4-8, 10, 13, 14, 26, 29, 34, 40 e 42)
- New Delhi Metallo-β-lactamases (NDM)
- OXA-23-like β-lactamase (include OXA-23, 49, 73, 134, 146, 165 – 171 e 225)
- OXA-48-like β-lactamase (include OXA- 48, 181, 204, 232, 244, 245 e 484) • OXA-51-like β-lactamase (include OXA-51, 66, 69, 87, 89, 106, 107, 108, 109, 242, 387 e 404)
- SME carbapenemase
- Carbapenem-hydrolysing oxacillinase OXA-58 (blaOXA-58) gene (OXA-58, OXA-97)
- Klebsiella pneumoniae carbapenemase (KPC)
- Imipenemase resistance (IMI-1, 2, 4, 7, 8 e NMC-A)
