+39 02 952451 segreteria@nlm.it

Coagulation

Multiplex Real Time

CVD-6 Multiplex Real Time

  • AA1397/48

CVD-6 Multiplex Real Time kit allows the detection and identification of 6 different mutations and polymorphisms involved in arterial and venous thrombosis. The kit is based on Real Time PCR technology and melting curve analysis.

Targets:
– Factor V G1691A
– Factor V H1299R
– Factor II G20210A
– MTHFR C677T
– MTHFR A1298C
– PAI-1 4G/5G

Interpretive software: Real Gene (DO022)
Full automation: sistema OMNIA
  • Real Time
  • 48
    test
  • CE IVD

Factor II

Factor II (G20210A) Real Time (FRET)

  • AA831

The kit allows the identification of the G20210A mutation in Factor II or prothrombin, through melting curve analysis.

Interpretive software: Real Gene (DO022)
  • Real Time
  • 50
    test
  • CE IVD

Factor II (G20210A) Real Time (FRET)

  • AA831/50A

The kit allows the identification of the G20210A mutation in Factor II or prothrombin, through melting curve analysis.

Interpretive software: Real Gene (DO022)
Full automation: sistema OMNIA
  • Real Time
  • 50
    test
  • CE IVD

Factor V

Factor V (G1691A) Real Time FRET

  • AA832

The kit allows the identification of the Factor V Leiden, caused by the mutation G1691A (R506Q) in Factor V, through melting curve analysis.

Interpretive software: Real Gene (DO022)
  • Real Time
  • 50
    test
  • CE IVD

FACTOR V (G1691A) Real Time (FRET)

  • AA832/50A

The kit allows the identification of the Factor V Leiden, caused by the mutation G1691A (R506Q) in Factor V, through melting curve analysis.

Interpretive software: Real Gene (DO022)
Full automation: sistema OMNIA
  • Real Time
  • 50
    test
  • CE IVD

MTHFR (C677T)

MTHFR (C677T) Real Time FRET

  • AA901

The kit allows the identification of the C677T mutation in MTHFR gene (methylenetetrahydrofolate reductase), through melting curve analysis.

Interpretive software: Real Gene (DO022)
  • Real Time
  • 25
    test
  • CE IVD

MTHFR (C677T) Real Time (FRET)

  • AA901/25A

The kit allows the identification of the C677T mutation in MTHFR gene (methylenetetrahydrofolate reductase), through melting curve analysis.

Interpretive software: Real Gene (DO022)
Full automation: sistema OMNIA
  • Real Time
  • 25
    test
  • CE IVD

MTHFR (A1298C)

MTHFR (A1298C) Real Time FRET

  • AA902

The kit allows the identification of the A1298C mutation in MTHFR gene (methylenetetrahydrofolate reductase), through melting curve analysis.

Interpretive software: Real Gene (DO022)
  • Real Time
  • 25
    test
  • CE IVD

MTHFR (A1298C) Real Time (FRET)

  • AA902/25A

The kit allows the identification of the A1298C mutation in MTHFR gene (methylenetetrahydrofolate reductase), through melting curve analysis.

Interpretive software: Real Gene (DO022)
Full automation: sistema OMNIA
  • Real Time
  • 25
    test
  • CE IVD

PAI 1

PAI 1 (4G/5G) Real Time FRET

  • AA1034

The kit allows the genotyping of the 4G/5G polymorphisms in the gene that encodes for the protein Plasminogen Activator Inhibitor-1 (PAI-1), through melting curve analysis.

Interpretive software: Real Gene (DO022)
  • Real Time
  • 25
    test
  • CE IVD

PAI 1 (4G/5G) Real Time FRET

  • AA1034/25A

The kit allows the genotyping of the 4G/5G polymorphisms in the gene that encodes for the protein Plasminogen Activator Inhibitor-1 (PAI-1), through melting curve analysis.

Interpretive software: Real Gene (DO022)
Full automation: sistema OMNIA
  • Real Time
  • 25
    test
  • CE IVD

Fattore V (H1299R)

Fattore V (H1299R) Real Time FRET

  • AA933

The kit allows the identification of the H1299R mutation in Factor V (HR2), through melting curve analysis. The aplotype HR2 leads to an increased risk of thrombosis when in association with FV Leiden.

Interpretive software: Real Gene (DO022)
  • Real Time
  • 50
    test
  • CE IVD

Multiplex RDB

CVD-14

  • AC084

The kit allows the identification of the main mutations and polymorphisms involved in arterial and venous thrombosis and in the lipid metabolism.
Targets:
– Factor V G1691A
– Factor V H1299R
– Factor II G20210A
– MTHFR C677T
– MTHFR A1298C
– CBS 844ins68 I/D
– PAI-1 4G/5G
– GPIIIa T1565C (HPA-1 a/b)
– ACE I/D
– AGT g.9543T>C (M235T)
– ATR-1 A1166C
– β-fibrinogen -455 G>A
– Factor XIII g.7130G>T (V34L)
– ApoE C112R and R158C

  • RDB
  • 20
    test
  • CE IVD

Screening test for thrombophilic disease 7 mutations

  • AC034

The kit allows the identification of the main mutations involved in thrombophilic diseases.
Targets:
– Factor V G1691A
– Factor V H1299R
– Fattore V Y1702C
– Factor II G20210A
– MTHFR C677T
– MTHFR A1298C
– PAI-1 4G/5G

  • RDB
  • 25
    test
  • CE IVD

Screening test for thrombophilic disease 3 mutations

  • AC082

The kit allows the identification of 3 mutations involved in thrombophilic diseases.
Targets:
– Factor V G1691A
– Factor II G20210A
– MTHFR C677T

  • RDB
  • 25
    test
  • CE IVD

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in accordance with current Decree of the Italian Ministry of Health of 26 January 2023 and guidelines of the Italian Ministry of Health.