Pharmacogenetics

DPYD

DPYD Real Time (FRET)

AA1579/48A

The kit allows the identification of 5 mutations in DPYD gene associated to clinically relevant adverse event to the chemioterapic agent
Mutations:
c.1905+1G>A
c.1679T>G
c.2846A>T
c.1129–5923C>G (variante in linkage disequilibrium con c.1236G>A)
c.2194G>A

Interpretive software: Real-PHARMA (DO041)

Full automation: sistema OMNIA

Real Time

48
test

CE IVD

Brochure

UGT1A1

UGT1A1 Real time (FRET)

AA1628/24A

The kit allows the identification of 4 allelic variants of UGT1A1 gene, associated to severe toxicity during the administration of irinotecan, an anti-tumoral drug.
In addition, the same variants are associated to altered metabolism of bilirubin in Gilbert’s syndrome.
Variants:
*1
*28
*36
*37