{"id":3750,"date":"2025-10-09T11:52:24","date_gmt":"2025-10-09T09:52:24","guid":{"rendered":"https:\/\/nlm.it\/?post_type=prodotto&#038;p=3750"},"modified":"2025-10-13T12:04:51","modified_gmt":"2025-10-13T10:04:51","slug":"ugt1a1-real-time-fret-plus","status":"publish","type":"prodotto","link":"https:\/\/nlm.it\/en\/prodotto\/ugt1a1-real-time-fret-plus\/","title":{"rendered":"UGT1A1 Real Time (FRET) Plus"},"content":{"rendered":"<p>The kit allows the detection and identification of five allelic variants of the UGT1A1 gene associated with severe toxicity following administration of irinotecan, a drug used in cancer treatment. Furthermore, these same variants are associated with altered bilirubin metabolism in Gilbert&#8217;s syndrome. Protocol applicable on the OMNIA system for extraction and PCR set-up.<br \/>\nDetected variants: *1, *28, *36, *37, *6<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The kit allows the detection and identification of five allelic variants of the UGT1A1 gene associated with severe toxicity following administration of irinotecan, a drug used in cancer treatment. Furthermore, these same variants are associated with altered bilirubin metabolism in Gilbert&#8217;s syndrome. Protocol applicable on the OMNIA system for extraction and PCR set-up. Detected variants: [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-3750","prodotto","type-prodotto","status-publish","hentry","prodotto-category-pharmacogenetics","prodotto-category-ugt1a1"],"acf":[],"_links":{"self":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/prodotto\/3750","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/prodotto"}],"about":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/types\/prodotto"}],"author":[{"embeddable":true,"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/comments?post=3750"}],"version-history":[{"count":0,"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/prodotto\/3750\/revisions"}],"wp:attachment":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/media?parent=3750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}