{"id":2688,"date":"2023-08-22T11:19:57","date_gmt":"2023-08-22T09:19:57","guid":{"rendered":"https:\/\/nlm.it\/prodotto\/ugt1a1-real-time-fret\/"},"modified":"2025-10-10T10:07:21","modified_gmt":"2025-10-10T08:07:21","slug":"ugt1a1-real-time-fret","status":"publish","type":"prodotto","link":"https:\/\/nlm.it\/en\/prodotto\/ugt1a1-real-time-fret\/","title":{"rendered":"UGT1A1 Real time (FRET)"},"content":{"rendered":"<p>The kit allows the identification of three allelic variants of UGT1A1 gene, associated to severe toxicity during the administration of irinotecan, an anti-tumoral drug.<br \/>\nIn addition, the same variants are associated to altered metabolism of bilirubin in Gilbert&#8217;s syndrome.<br \/>\n<strong>Variants:<\/strong><br \/>\n*1<br \/>\n*28<br \/>\n*36<br \/>\n*37<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The kit allows the identification of three allelic variants of UGT1A1 gene, associated to severe toxicity during the administration of irinotecan, an anti-tumoral drug. In addition, the same variants are associated to altered metabolism of bilirubin in Gilbert&#8217;s syndrome. Variants: *1 *28 *36 *37<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-2688","prodotto","type-prodotto","status-publish","hentry","prodotto-category-genetics-diseases","prodotto-category-pharmacogenetics","prodotto-category-ugt1a1"],"acf":[],"_links":{"self":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/prodotto\/2688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/prodotto"}],"about":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/types\/prodotto"}],"author":[{"embeddable":true,"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/comments?post=2688"}],"version-history":[{"count":0,"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/prodotto\/2688\/revisions"}],"wp:attachment":[{"href":"https:\/\/nlm.it\/en\/wp-json\/wp\/v2\/media?parent=2688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}